According to the new consumer report of Blue Cave, on October 27th, according to foreign news reports, the research funded by the National Institute of Health showed the destructive effects of electronic cigarettes and smoking on blood vessels, and the combination of electronic cigarettes and ordinary cigarettes may increase health risks.

Long -term use of electronic cigarettes or electronic cigarette products can significantly damage the function of human blood vessels and increase the risk of cardiovascular disease. In addition, compared with any of the products alone, using electronic cigarettes and ordinary cigarettes may lead to greater risks. These discovers are supported by two new studies supported by the National Institute of Cardiopulmonary Hematology (NHLBI) under the National Institute of Health (NIH).

These findings are published today in the magazine of "arteriosclerosis, thrombosis, and vascular biology", adding more and more evidence to indicate that long -term use of electronic cigarettes will damage a person's health.

Over the years, researchers have known that smoking will cause damage to blood vessels. However, people have little influence on electronic cigarettes on cardiovascular health. These two new studies -one for humans and the other for mouse -aims to change this situation.

"In our human research, we found that the vascular function of chronic electronic cigarette users is damaged, which may increase their risk of heart disease." Dr. Matthew L. Springer, a medical professor in the department, said Doctorate of disease is also the person in charge of these two studies. "This indicates that the long -term users of electronic cigarettes may encounter the risk of vascular disease similar to long -term smokers."

In the first study, Springer and his colleagues collected blood samples from a group of 120 volunteers. These volunteers include those who have long -term use of electronic cigarettes, long -term smoking, and non -electronic cigarettes. Researchers define long -term use of electronic cigarettes to more than 5 times a week, which lasted more than three months, and defined long -term use of cigarettes to smoke more than 5 daily.

Then, they exposed each blood sample to the human blood vessel (endothelial) cells cultivated in the laboratory and measured the release of nitric oxide. Nitrogen dioxide is a chemical tag to evaluate the normal function of endothelial cells. They also tested cell permeability, that is, molecules through one layer of cells to reach the other side. Excessive permeability can leak vascular leakage, which will damage the function and increase the risk of cardiovascular disease.

Researchers have found that nitrogen oxide produced by vascular cells using electronic cigarettes and smokers has a significant decrease in blood oxide from vascular cells than those who do not use electronic cigarettes.

It is worth noting that researchers have found that compared with the blood of smokers and non -smokers, the blood of people using electronic cigarettes has higher permeability to vascular cells. The blood of people using electronic cigarettes is also more hydrogen peroxide than the blood of people who do not suck electronic cigarettes. Researchers say that each of these three factors may cause the blood vessel function of people using electronic cigarettes.

In addition, Springer and his team found that the harmful effect of electronic cigarettes on cardiovascular is different from tobacco tobacco. Specifically, they found that the level of circulating biomarkers in certain cardiovascular risks in the blood of smokers is higher, and the level of circulating biomarkers in other cardiovascular risk in the blood of people using electronic cigarettes is higher.

"These findings show that, compared with these two products alone, using these two products with many people may increase their health risks," Siplinger said. "We didn't expect to see this."

In the second study, researchers tried to find out whether the specific ingredients of cigarette smoke or electronic smoke steam would cause vascular damage. In the research of mice, they exposed animal to various substances found in tobacco smoke or electronic smoke. These include nicotine, mint (a cigarette additive), gases, and acetaldehyde (two chemicals found in both tobacco smoke and electronic smoke steam), as well as the granular carbon that represents the granularity of smoke and electronic smoke steam Nano particles.

Using special arterial flow measurement, researchers have proved that vascular damage does not seem to be caused by the specific component of cigarette smoke or electronic smoke steam. On the contrary, they said that this seems to be caused by airway stimulation. This stimulus will trigger biological signals in the virgin nerves and cause vascular damage in some way, which may be through the inflammation process. The vagus nerve is a long nerve extending from the brain, connecting the airway into other parts of the nervous system, and play a key role in heart rate, breathing and other functions. Researchers have shown that separation of rats can prevent vascular injury caused by tobacco tobacco, which proves its key role in this process.

"We were surprised to find that no ingredients could be removed to prevent the damage of smoke or steam on blood vessels," Siplinger said. "As long as there are irritants in the airway, the function of the vascular function may be damaged."

This discovery is of great significance to the efforts of supervision tobacco products and electronic cigarettes, because it emphasizes how difficult it is to determine any of them that causes vascular injury. "What I want to tell people is: the air with clean breathing, avoid using these products," Springer said.

Dr. Lisa Postow, an official NHLBI project official of the NHLBI lung disease department, agreed to provide further evidence that the contact of the electronic cigarette may cause harmful cardiovascular health. She added that more data is needed to fully understand the impact of electronic cigarettes on health. NIH and other agencies are continuing to explore this field.

Regarding the National Celobiopsis Institute (NHLBI): NHLBI is a global leader who conducts and supports the study of cardiopulmonary blood diseases and sleep disorders. These studies have promoted the development of scientific knowledge, improved public health, and saved life.

Regarding the National Institute of Health (NIH): The National Institute of Health (NIH) is a medical research institution in the United States, including 27 research institutes and centers, and is an integral part of the US Department of Health and Public Service. NIH is the main federal institution to carry out and support the foundation, clinical and transforming medical research, and is investigating the causes, treatment and treatment methods of common and rare diseases.